True Zero Technologies, a veteran-owned small business, was founded on the principle that the purposeful enablement of people and technology in an organization directly ties to the quality of its outcomes. True Zero recognizes that those outcomes begin and end with our people, and that is what we have built a community of like-minded, driven, and passionate individuals and innovators who are aligned in a common goal of delivering top-tier services to our customers. Our culture and commitment have been recognized through numerous accolades, including being named one of the Best Places to Work in 2023 in two categories (“Prosperous and Thriving” ($5MM–$50MM in gross revenue) and “Mid-Atlantic Region” (DC, DE, MD, NC, VA, WV)), and again in 2025 as a Best Places to Work honoree. In addition, True Zero earned coveted spots on the Inc. 5000 list of fastest-growing companies in America in 2022, 2023, and 2025, a testament to our sustained growth driven by our people-first approach and unwavering dedication to excellence.
True Zero is seeking an Information System Security Officer (ISSO) to support cybersecurity governance and Risk Management Framework (RMF) activities for enterprise information systems at the National Institutes of Health (NIH). Working under the direction of the Senior ISSO, this position partners with System Owners, engineers, cybersecurity operations personnel, and Government stakeholders to maintain the security posture and authorization readiness of assigned systems.
The ISSO is responsible for coordinating the day to day execution of RMF activities, maintaining security documentation, supporting continuous monitoring, tracking remediation efforts, and ensuring cybersecurity activities remain aligned with Federal requirements throughout the system lifecycle. This role requires strong organizational skills and the ability to coordinate activities across multiple technical disciplines while serving as a trusted advisor to system stakeholders.
We’re actively searching for talented security and technology practitioners who are ready to experience the True Zero difference. As a True Zero team member, you'll enjoy:
- Competitive salary, paid twice per month
- Best in class medical coverage
- 100% of medical premiums covered by True Zero
- Company wide new business incentive programs
- Contribution Incentives (i.e. white papers, blog posts, internal webinars, etc.)
- 3 weeks of PTO starting + 11 Paid Holidays Annually
- 401k Program with 100% company match on the first 4%
- Monthly reimbursement of Cell Phone and Home Internet costs
- Paternity/Maternity Leave
- Investment in training and certifications to broaden and deepen your technical skills
- Coordinate enterprise remediation activities for vulnerabilities identified through continuous monitoring, vulnerability scanning, penetration testing, audits, and security assessments.
- Develop, maintain, and manage POA&Ms in accordance with Federal, HHS, and NIH requirements.
- Partner with ISSOs, system owners, security engineers, and technical teams to establish remediation plans, milestones, and completion timelines.
- Monitor remediation progress, validate supporting evidence, and ensure corrective actions are accurately documented.
- Coordinate risk acceptance requests, compensating controls, waivers, and remediation exceptions through established governance processes.
- Track remediation performance against established service level objectives and communicate overdue or high priority items to program leadership.
- Support RMF authorization activities by ensuring vulnerabilities and POA&M items are accurately reflected within authorization documentation.
- Collaborate with vulnerability management and threat intelligence personnel to reprioritize remediation activities based on exploitability, Known Exploited Vulnerabilities (KEVs), operational impact, and emerging threats.
- Develop recurring remediation status reports, executive summaries, and operational metrics for Government leadership.
- Support internal and external cybersecurity assessments by coordinating remediation responses and tracking corrective actions through closure.
- Recommend process improvements that enhance remediation efficiency, reporting accuracy, and enterprise risk reduction.
- Bachelor’s degree in Cybersecurity, Information Systems, Information Technology, or a related discipline.
- Three or more years of experience supporting vulnerability management, RMF, cybersecurity governance, or compliance programs.
- Experience developing and managing Plans of Action and Milestones (POA&Ms).
- Working knowledge of the NIST Risk Management Framework (RMF), FISMA, and NIST SP 800-53.
- Experience coordinating remediation activities across multiple technical teams and business stakeholders.
- Strong organizational skills with the ability to manage multiple concurrent remediation efforts.
- Excellent written and verbal communication skills, including experience preparing reports for technical and executive audiences.
Preferred Qualifications:
- Experience supporting NIH, HHS, or other Federal civilian agencies.
- Experience with enterprise GRC platforms such as JCAM, eMASS, ServiceNow, Archer, or similar governance tools.
- Experience supporting vulnerability management programs and Continuous Diagnostics and Mitigation (CDM) initiatives.
- Familiarity with CISA Known Exploited Vulnerabilities (KEV) guidance, Binding Operational Directives, and Federal remediation requirements.
- Experience supporting audit remediation, authorization package development, and continuous monitoring programs.
Preferred Certifications:
One or more of the following is preferred:
- Certified in Governance, Risk and Compliance (CGRC)
- CISSP
- Security+
- CAP
- CISM
- Project Management Professional (PMP)