This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.
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Provide hands-on support to small-scale and scale-up experiments and overall development of the Cellares advanced cell therapy manufacturing platform
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Interpret and adapt a cell therapy manufacturing process from a client to the Cellares platform; design and execute experiments related to workflow development and scale-up
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Develop process diagrams and flowcharts for novel and existing processes
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Create project plans, timelines, and reports to inform project execution; address blockers and challenges during execution
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Perform primary cell line maintenance and leukopak processing, including isolation, activation, gene modification, expansion and cryopreservation
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Draft and review work instructions, standard operating procedures, test plans, and reports
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Generate and review process documentation including but not limited to Manufacturing Batch Records and Bill of Materials (BOM)
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Analyze and interpret process data, prepare presentations and present technical results
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Identify and investigate process deviations and non-conformances, document findings and implement effective corrective and preventive actions
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BS or MS in Bioengineering, Chemical Engineering, Biology, Biochemistry, or related field with 4-10 years of process development experience in the cell and gene therapy field
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Experience in aseptic technique and primary immune cell culture
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Extensive experience using and troubleshooting semi-automated instruments and laboratory information management systems
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Strong problem-solving skills and attention to detail
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Strong technical writing skills and experience authoring SOPs and reports
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Familiarity with cell therapy analytical testing methods, such as flow cytometry and cell-based assays is preferred
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Creative, self-motivated, eager to take on a wide variety of tasks and grow with evolving technology
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Self-awareness, integrity, authenticity, and a growth mindset