About this role
The Opportunity
Maze is looking for a Director of Statistical Progr ammi ng , who will help shap e the data foundation of our clinical development programs . In thi s role y ou’ll collaborate closely with colleagues across Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to keep our studies rigorous, high-quality, and ready for regulatory review .
You’ll report to the Vice President of Biometrics and lead the stra tegy and day-to-day execution of statistical programmi ng across multiple clinical studies . You r leadership will ensure we deliver reliable, efficient , and regulatory-c ompliant programming outputs that drive smarter decisions and ad vance our therapeutic programs.
The Impact You’ll Have
• Define and implement statistical programming strategy , standards, and best practices across development programs .
• Lead the design, development, validation , and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM, ADaM datasets, TLFs) .
• Ensure programming infrastructure is robust , scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11, GxP ), and supports reproducibility and audit readiness .
• Drive automation and standardization of programming workflows to improve efficiency and consistency across studies .
• Partner closely with Biostatistics, Clinical Data Management, Regulatory Affairs , and IT to define programming requirements, align on analysis/reporting deliverables, and ensure data integrity .
• Represent the statistical programming function in cross-functional meetings and strategic initiatives .
• Manage CROs and external programming vendors , including scope, timelines, quality, and budget oversight .
• Support outsourcing strategy and vendor selection
As a Director , we also expect you to demonstrate the following Leadership Competencies:
• Communication and Influence
• Builds communication channels across Maze for sharing information.
• Influences Senior Management decisions through persuasive arguments.
• Respectfully addresses differing opinions leading to support of decisions.
• Teamwork and Collaboration
• Champions partnerships and connections across Maze.
• Proactively addresses issues that could result in breakdown of team relationships.
• Spotlights team and individual contributions in public forums.
• Execution and Results
• Addresses gaps and leverages strengths to get best results.
• Maintains a steadying presence and clarifies priorities during change.
• Anticipates and removes barriers that put functional/corporate goals at risk.
• Develop Others and Self
• Remove barriers to staff development and empowers them to make their own decisions.
• Stays current on industry trends and keeps direct-reports prepared and responsive.
What We’re Looking For
• An advanced degree in Statistics, Computer Science, Mathematics, or related discipline
• Master’s degree with 10+ years of experience, or Ph.D. with 8+ years of experience
• A track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.
• Strong decision-making skills and the a bility to guide teams through ambiguity while influencing across project teams.
• A collaborative leadership style that emphasizes mentorship, knowledge sharing, and developing others.
• Deep technical expertise in statistical programming for clinical research, with familiarity in CDISC standards, submission ‑ ready deliverables, and modern programming best practices.
This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $229, 000 - $279,000 . Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
#LI-Hybrid
Maze is looking for a Director of Statistical Progr ammi ng , who will help shap e the data foundation of our clinical development programs . In thi s role y ou’ll collaborate closely with colleagues across Biostatistics, Clinical Data Management, Clinical Operations, and Regulatory Affairs, and oversee external vendors to keep our studies rigorous, high-quality, and ready for regulatory review .
You’ll report to the Vice President of Biometrics and lead the stra tegy and day-to-day execution of statistical programmi ng across multiple clinical studies . You r leadership will ensure we deliver reliable, efficient , and regulatory-c ompliant programming outputs that drive smarter decisions and ad vance our therapeutic programs.
The Impact You’ll Have
• Define and implement statistical programming strategy , standards, and best practices across development programs .
• Lead the design, development, validation , and maintenance of SAS macros, scripts, and applications supporting clinical data analysis, reporting, and regulatory deliverables (e.g., SDTM, ADaM datasets, TLFs) .
• Ensure programming infrastructure is robust , scalable, and compliant with regulatory standards (e.g., FDA 21 CFR Part 11, GxP ), and supports reproducibility and audit readiness .
• Drive automation and standardization of programming workflows to improve efficiency and consistency across studies .
• Partner closely with Biostatistics, Clinical Data Management, Regulatory Affairs , and IT to define programming requirements, align on analysis/reporting deliverables, and ensure data integrity .
• Represent the statistical programming function in cross-functional meetings and strategic initiatives .
• Manage CROs and external programming vendors , including scope, timelines, quality, and budget oversight .
• Support outsourcing strategy and vendor selection
As a Director , we also expect you to demonstrate the following Leadership Competencies:
• Communication and Influence
• Builds communication channels across Maze for sharing information.
• Influences Senior Management decisions through persuasive arguments.
• Respectfully addresses differing opinions leading to support of decisions.
• Teamwork and Collaboration
• Champions partnerships and connections across Maze.
• Proactively addresses issues that could result in breakdown of team relationships.
• Spotlights team and individual contributions in public forums.
• Execution and Results
• Addresses gaps and leverages strengths to get best results.
• Maintains a steadying presence and clarifies priorities during change.
• Anticipates and removes barriers that put functional/corporate goals at risk.
• Develop Others and Self
• Remove barriers to staff development and empowers them to make their own decisions.
• Stays current on industry trends and keeps direct-reports prepared and responsive.
What We’re Looking For
• An advanced degree in Statistics, Computer Science, Mathematics, or related discipline
• Master’s degree with 10+ years of experience, or Ph.D. with 8+ years of experience
• A track record of leading statistical programming efforts across multiple clinical studies or regulatory submissions.
• Strong decision-making skills and the a bility to guide teams through ambiguity while influencing across project teams.
• A collaborative leadership style that emphasizes mentorship, knowledge sharing, and developing others.
• Deep technical expertise in statistical programming for clinical research, with familiarity in CDISC standards, submission ‑ ready deliverables, and modern programming best practices.
This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week.
About Maze Therapeutics
Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease.
Our People
Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.
Our Core Values
Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.
Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others.
Stand True – Our integrity is foundational; it guides us no matter the obstacle.
The expected annual salary range for employees located in the San Francisco Bay Area is $229, 000 - $279,000 . Additionally, this position is eligible for an annual performance bonus.
Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future.
Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy.
#LI-Hybrid
About Maze Therapeutics
Maze Therapeutics is hiring for the director, statistical programming role. NewJob aggregates active openings directly from Maze Therapeutics's applicant tracking system, so this listing is current.
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